protein expression levels of the stat gene family (Human Protein Atlas)
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Protein Expression Levels Of The Stat Gene Family, supplied by Human Protein Atlas, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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1) Product Images from "Bioinformatics Analysis of Expression Profiles and Prognostic Values of the Signal Transducer and Activator of Transcription Family Genes in Glioma"
Article Title: Bioinformatics Analysis of Expression Profiles and Prognostic Values of the Signal Transducer and Activator of Transcription Family Genes in Glioma
Journal: Frontiers in Genetics
doi: 10.3389/fgene.2021.625234
Figure Legend Snippet: mRNA expression of the STAT gene family in different types of cancers (analyzed with Oncomine database). Search parameters were: fold change = 2, P -value = 0.01. The value in the tables represents the number of datasets that conform to the thresholds. The color intensity (red or blue) is positively related to the degree of upregulation or downregulation, respectively. The mRNA expression of the STAT gene family in glioma is sketched with green highlights.
Techniques Used: Expressing
Figure Legend Snippet: mRNA expression levels of STATs in glioma (using TCGA database). (A–G) mRNA expression levels of STAT genes in LGG and GBM ( ∗∗ p < 0.01 and ∗∗∗ p < 0.001). (H) Co-expression heat map of STAT genes in glioma. (I–O) Correlation between STAT genes expression and IDH mutation status in glioma ( ∗∗ p < 0.01 and ∗∗∗ p < 0.001). “NS” means “not significant” or “not statistically significant,” i.e., p ≥ 0.05.
Techniques Used: Expressing, Mutagenesis
Figure Legend Snippet: mRNA expression levels of STATs in glioma (CGGA). (A–G) mRNA expression levels of STAT genes in LGG and GBM using CGGA database ( ∗∗ p < 0.01, and ∗∗∗ p < 0.001). (H) Co-expression heat map of STAT genes in glioma using CGGA database. (I–O) The correlation between STAT gene expression and IDH mutation status in glioma using CGGA database ( ∗∗ p < 0.01 and ∗∗∗ p < 0.001). “NS” means “not significant” or “not statistically significant,” i.e., p ≥ 0.05.
Techniques Used: Expressing, Gene Expression, Mutagenesis
Figure Legend Snippet: Protein expression level and genetic alteration of STATs in glioma . (A) The protein expression of STAT genes in glioma (low grade and high grade) and normal brain tissues using human protein atlas database. (B) Genetic variations of STAT genes in glioma using OncoPrint.
Techniques Used: Expressing
Figure Legend Snippet: Prognostic values of STATs in glioma. (A–G) Prognostic significance of individual STAT genes in glioma using TCGA database. (H–N) Survival curves of individual STAT genes in glioma using CGGA database.
Techniques Used:
Figure Legend Snippet: Construction of a prognostic gene signature model based on the STAT gene family. ( A–D) Construction of a new prognostic signature. (E) Prognostic value of the new signature in glioma using TCGA database. (F) Prognostic value of the new signature in glioma using CGGA database.
Techniques Used:
Figure Legend Snippet: Correlation analysis between STAT genes and TIICs. (A) Correlation between STATs and each type of TIICs (B-cells, CD4 + T-cells, CD8 + T-cells, neutrophils, macrophages, and dendritic cells) in LGG; (B) Correlation between STATs and each type of TIICs (B-cells, CD4 + T-cells, CD8 + T-cells, neutrophils, macrophages, and dendritic cells) in GBM.
Techniques Used: